ea0026p104 | Female reproduction | ECE2011
Machelon V
, Redjimi N
, Gaudin F
, Delbos L
, Emilie D
, Prevot S
, Balabanian K
Little is known about the molecules that contribute to tumor growth in epithelial ovarian cancer (EOC) that remain the most lethal gynecological neoplasm. Glucocorticoid-Induced Leucine Zipper (GILZ), a leucine zipper protein of 17 kDa, is frequently detected in epithelial tissues with a hormonal background. We detected GILZ in EOC1 and we further demonstrated that this factor which expression is enhanced by estradiol (E2), activates tumor cell proliferat...